Couple of quick things:

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Tolerance

Costs of Resistance

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Induced resistance can be costly

Fitness Costs of Mutations Affecting the Systemic Acquired Resistance Pathway in Arabidopsis thaliana Heidel et al 2004 Genetics 168, 2197-2206

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How about R-genes?

Maintaining R-genes may be costly

How to compare plants with/without a resistance gene

How to compare plants with/without a resistance gene

Used a Cre/lox system

Looked at presence/absence of RPM1

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Rpw8 has a cost in absence of pathogen

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Some of the transformants looked like this

Why might this occur

R-protiens require other host factors for proper folding

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Other evidence for this phenomenon

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Balancing selection implies different alleles are beneficial in different situations

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Bergelson pers. com.

Are all R-genes polymorphic anyway?

Costs of Quantitative Risistance

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